ZKSCAN3 Antibody

Catalog Number:	43570
other_names:	ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1.
Amount:	100μg
calculated_mw:
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#: Q9BRR0 NCBI Gene ID: 80317
Form of Antibody:	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage/Stability:
Immunogen:	Fusion protein of human ZKSCAN3
Purification:	Antigen affinity purification
Specificity/Sensitivity:	The antibody detects endogenous levels of total ZKSCAN3 protein.
Applications:	IHC
Background:	Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.
References:
appl_detail:	Immunohistochemistry: 1: 20-100
	Datasheet PDF

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