POLDIP3 Antibody

Catalog Number:

43556

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BY77
NCBI Gene ID: 84271

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human POLDIP3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total POLDIP3 protein.

Applications:

WB

Background:

POLDIP3 (polymerase delta-interacting protein 3), also known as SKAR or PDIP46, is a 421 amino acid nuclear protein. POLDIP3 interacts with DNA pol ? 2, a protein essential to DNA replication, recombination and repair. POLDIP3 is a substrate for the signaling intermediate Rsk-1 and is thought to regulate cell growth. POLDIP3 contains one RRM (RNA recognition motif) domain and is phosphorylated upon DNA damage. POLDIP3 is ubiquitously expressed with highest levels found in heart, kidney, skeletal muscle and brain. Due to alternative splicing, POLDIP3 is expressed as two isoforms.

References:

appl_detail:

Western blotting: 1:200-1000

Datasheet PDF