TIA1 Antibody

Catalog Number:

43541

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P31483
NCBI Gene ID: 7072

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total TIA1 protein.

Applications:

IHC WB

Background:

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

References:

appl_detail:

Western blotting: 1:500-2000
Immunohistochemistry: 1: 100-250

Datasheet PDF