ITGA4 Antibody

Catalog Number:

43510

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P13612
NCBI Gene ID: 3676

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human ITGA4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total ITGA4 protein.

Applications:

IHC

Background:

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF