NRAS/HRAS/KRAS Antibody

Catalog Number:

43477

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P01111
Gene ID:4893

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.10~60 derived from Human NRAS/HRAS/KRAS.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total NRAS/HRAS/KRAS protein.

Applications:

WB

Background:

 Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation.

 

Taparowsky E., Shimizu K., Goldfarb M., Wigler M.Cell 34:581-586(1983)

Reddy E.P.Science 220:1061-1063(1983) 

Shimizu K., Birnbaum D., Ruley M.A., Fasano O., Suard Y., Edlund L., Taparowsky E., Goldfarb M., Wigler M. Nature 304:497-500(1983)

 

References:

appl_detail:

 Western blotting: 1:500-1:1000

Datasheet PDF