TNNC1 Antibody

Catalog Number:

43381

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P63316
Gene ID: 7134

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human TNNC1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TNNC1 protein.

Applications:

WB IHC

Background:

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.

References:

appl_detail:

Western blotting: 1:500-1:2000

Immunohistochemistry: 1:20-1:100

Datasheet PDF