1-832-868-1888
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Catalog Number: |
43328 |
| other_names: | DKFZp564O1016; FLJ42398; MGC27076; SENP5; Sentrin-specific protease 5 |
Amount: |
100μg |
| calculated_mw: | 87kd |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: Q96HI0 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Fusion protein of human SENP5 |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total SENP5 protein. |
Applications: |
WB |
Background: |
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates. |
References: |
|
appl_detail: |
Western blotting: 1:500-1:2000 |
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