DCX Antibody

Catalog Number:

43298

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O43602
Gene ID: 1641

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human DCX

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DCX protein.

Applications:

WB IHC

Background:

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:20-1:100

Datasheet PDF