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CCNT2 Antibody

Catalog Number:

43292
other_names: CYCT2

Amount:

100μg
calculated_mw: 81kd
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60583
Gene ID: 905

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human CCNT2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CCNT2 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

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