CTSK Antibody

Catalog Number:

43232

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P43235
Gene ID: 1513

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human CTSK

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CTSK protein.

Applications:

IHC

Background:

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF