VAV3 Antibody

Catalog Number:

43646

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UKW4
NCBI Gene ID: 10451

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human VAV3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total VAV3 protein.

Applications:

IHC

Background:

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF