SETMAR Antibody

Catalog Number:

43086

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q53H47
Gene ID: 6419

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human SETMAR

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SETMAR protein.

Applications:

WB IHC

Background:

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:20-1:100

Datasheet PDF