GAMT Antibody

Catalog Number:

43076

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14353
Gene ID: 2593

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human GAMT

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GAMT protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:200

Datasheet PDF