TXNL1 Antibody

Catalog Number:

43055

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O43396
Gene ID: 9352

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human TXNL1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TXNL1 protein.

Applications:

WB IHC

Background:

TXNL1 (Thioredoxin-like protein 1), also known as TRP32, TXL or TXL-1, is a 289 amino acid cytoplasmic protein that is thought to participate in endocytotic signaling pathways and may act as a redox sensor. Expressed throughout the body, TXNL1 functions to couple oxidative stress to endocytosis, thereby regulating the GDI:Rad5-mediated endocytic response. Additionally, overexpression of TXNL1 inhibits cell proliferation by predisposing the cell to G0/G1 arrest, suggesting that TXNL1 also functions as a transcriptional repressor.?

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:200

Datasheet PDF