QDPR Antibody

Catalog Number:

43037

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P09417
Gene ID: 5860

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human QDPR

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total QDPR protein.

Applications:

WB IHC

Background:

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.?

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF