UNCX Antibody

Catalog Number:

43839

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: A6NJT0
NCBI Gene ID: 340260

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human UNCX

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total UNCX protein.

Applications:

IHC

Background:

UNCX (UNC homeobox), also known as UNCX4.1, is a 531 amino acid nuclear transcription factor involved in neurogenesis and somitogenesis. Containing one homeobox DNA-binding domain, UNCX belongs to the paired homeobox family and UNC4 subfamily. UNCX assists in the formation of connections between hypothalamic neurons and the pituitary, which is necessary for central neurons to deliver hormones into peripheral blood. UNCX also plays a role in maintaining differentiation of the axial skeleton and acts upstream of Pax-9. The gene encoding UNCX maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF