WFS1 Antibody

Catalog Number:

43590

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O76024
NCBI Gene ID: 7466

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human WFS1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total WFS1 protein.

Applications:

IHC

Background:

This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF