BCL7A Antibody

Catalog Number:

42922

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q4VC05
Gene ID: 605

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human BCL7A

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total BCL7A protein.

Applications:

IHC

Background:

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF