POMK Antibody

Catalog Number:

42921

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H5K3
Gene ID: 84197

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human POMK

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total POMK protein.

Applications:

IHC

Background:

This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants.?

References:

appl_detail:

Immunohistochemistry: 1:100-1:200

Datasheet PDF