UBXN2B Antibody

Catalog Number:

42918

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14CS0
Gene ID: 137886

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human UBXN2B

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total UBXN2B protein.

Applications:

IHC

Background:

UBXD2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein that contains one UBX domain and one SEP domain. UBXN2B is required for ER and Golgi biogenesis and also plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis. Through interaction with VCP, UBXN2B forms a complex that has membrane fusion activity. Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity.

References:

appl_detail:

Immunohistochemistry: 1:100-1:200

Datasheet PDF