PCID2 Antibody

Catalog Number:

42887

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q5JVF3?
Gene ID: 55795

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human PCID2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PCID2 protein.

Applications:

WB IHC

Background:

PCID2 is expressed in immature and early-stage B lymphocytes and regulates expression of the mitotic checkpoint protein MAD2. Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:20-1:100

Datasheet PDF