WDR77 Antibody

Catalog Number:

42856

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BQA1
Gene ID: 79084

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human WDR77

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total WDR77 protein.

Applications:

WB IHC

Background:

WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF