VDAC3 Antibody

Catalog Number:

42830

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y277
Gene ID: 7419

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human VDAC3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total VDAC3 protein.

Applications:

WB IHC

Background:

This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:200

Datasheet PDF