UBE2B Antibody

Catalog Number:

42801

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P63146
Gene ID: 7320

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human UBE2B

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total UBE2B protein.

Applications:

IHC

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.

References:

appl_detail:

Immunohistochemistry: 1:100-1:200

Datasheet PDF