KEAP1 Antibody

Catalog Number:

42790

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14145
Gene ID: 9817

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human KEAP1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KEAP1 protein.

Applications:

IHC

Background:

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF