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RPA2 Antibody

Catalog Number:

42740
other_names: REPA2; RPA32; RP-A p32; RP-A p34

Amount:

100μg
calculated_mw: 29kd
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P15927
Gene ID: 6118

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human RPA2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RPA2 protein.

Applications:

WB IHC

Background:

Replication protein A 32 kDa subunit?is a?protein?that in humans is encoded by theRPA2?gene. As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

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