RHEB Antibody

Catalog Number:

42737

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q15382
Gene ID: 6009

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human RHEB

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RHEB protein.

Applications:

IHC

Background:

This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.

References:

appl_detail:

Immunohistochemistry: 1:30-1:150

Datasheet PDF