PTRH2 Antibody

Catalog Number:

42725

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y3E5
Gene ID: 51651

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human PTRH2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PTRH2 protein.

Applications:

WB IHC

Background:

PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis.?

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:25-1:100

Datasheet PDF