BAG family molecular chaperone regulator 5 Polyclonal Antibody

Catalog Number:

42692

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UL15

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human BAG family molecular chaperone regulator 5 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total BAG family molecular chaperone regulator 5 polyclonal antibody.

Applications:

WB

Background:

Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 By similarity. May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.

References:

[1]"The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange."Arakawa A., Handa N., Ohsawa N., Shida M., Kigawa T., Hayashi F., Shirouzu M., Yokoyama S.Structure 18:309-319(2010). [2]"Hi

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF