Caspase-7 Polyclonal Antibody;

Catalog Number:

42594

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P55210

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Caspase-7 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Caspase-7 polyclonal antibody;.

Applications:

WB

Background:

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.

References:

[1] "Mch3, a novel human apoptotic cysteine protease highly related to CPP32."Fernandes-Alnemri T., Takahashi A., Armstrong R.C., Krebs J., Fritz L.C., Tomaselli K.J., Wang L., Yu Z., Croce C.M., Salveson G., Earnshaw W.C., Litwack G., Alnemri E.S.Cancer

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF