1-832-868-1888
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Catalog Number: |
42573 |
| other_names: | Metavinculin, VCL, |
Amount: |
100μg |
| calculated_mw: | 125kd |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: P18206 |
Form of Antibody: |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Storage/Stability: |
|
Immunogen: |
Recombinant human Vinculin protein |
Purification: |
Caprylic Acid Ammonium Sulfate Precipitation purified |
Specificity/Sensitivity: |
The antibody detects endogenous level of total Vinculin polyclonal antibody. |
Applications: |
WB |
Background: |
Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion. |
References: |
[1] "Complete sequence of human vinculin and assignment of the gene to chromosome 10."Weller P.A., Ogryzko E.P., Corben E.B., Zhidkova N.I., Patel B., Price G.J., Spurr N.K., Koteliansky V.E., Critchley D.R.Proc. Natl. Acad. Sci. U.S.A. 87:566 |
appl_detail: |
Western blotting: 1:500 - 1:1000 |
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