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Vinculin Polyclonal Antibody

Catalog Number:

42573
other_names: Metavinculin, VCL,

Amount:

100μg
calculated_mw: 125kd
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P18206

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Vinculin protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Vinculin polyclonal antibody.

Applications:

WB

Background:

Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.

References:

[1] "Complete sequence of human vinculin and assignment of the gene to chromosome 10."Weller P.A., Ogryzko E.P., Corben E.B., Zhidkova N.I., Patel B., Price G.J., Spurr N.K., Koteliansky V.E., Critchley D.R.Proc. Natl. Acad. Sci. U.S.A. 87:566

appl_detail:

Western blotting: 1:500 - 1:1000

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