Macrophage metalloelastase Polyclonal Antibody

Catalog Number:

42560

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P39900

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Macrophage metalloelastase protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Macrophage metalloelastase polyclonal antibody.

Applications:

WB

Background:

May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

References:

[1]Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages.Shapiro S.D., Kobayashi D.K., Ley T.J.J. Biol. Chem. 268:23824-23829(1993)[2]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., M

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF