Keratin, type I cytoskeletal 18 Polyclonal Antibody

Catalog Number:

42526

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P05783

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant Human Keratin, type I cytoskeletal 18 chain protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Keratin, type I cytoskeletal 18 polyclonal antibody.

Applications:

WB IHC

Background:

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells By similarity. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

References:

[1] Comparison of mouse and human keratin 18: a component of intermediate filaments expressed prior to implantation.Oshima R.G., Millan J.L., Cecena G.Differentiation 33:61-68(1986) [2] Identification of a cell proliferation-inducing gene.Kim J.W.Submi

appl_detail:

Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200

Datasheet PDF