Tumor necrosis factor receptor superfamily member 10D Polyclonal Antibody

Catalog Number:

42499

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UBN6

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Tumor necrosis factor receptor superfamily member 10D protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Tumor necrosis factor receptor superfamily member 10D polyclonal antibody.

Applications:

IHC

Background:

Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to Ref.1, it cannot but according to Ref.2, it can induce the NF-kappa-B pathway.

References:

[1] "A novel receptor for Apo2L/TRAIL contains a truncated death domain."Marsters S.A., Sheridan J.P., Pitti R.M., Huang A., Skubatch M., Baldwin D., Yuan J., Gurney A., Goddard A.D., Godowski P., Ashkenazi A.Curr. Biol. 7:1003-1006(1997) [2] "The nove

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF