Tumor necrosis factor ligand superfamily member 10 Polyclonal Antibody

Catalog Number:

42488

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P50591

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Tumor necrosis factor ligand superfamily member 10 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Tumor necrosis factor ligand superfamily member 10 polyclonal antibody.

Applications:

IHC

Background:

Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.

References:

[1]"Identification and characterization of a new member of the TNF family that induces apoptosis." Wiley S.R., Schooley K., Smolak P.J., Din W.S., Huang C.-P., Nicholl J.K., Sutherland G.R., Davis-Smith T., Rauch C., Smith C.A., Goodwin R.G.Immunity 3:6

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF