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Interstitial collagenase Polyclonal Antibody

Catalog Number:

42473
other_names: Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1

Amount:

100μg
calculated_mw: 51kd
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P03956

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Interstitial collagenase polyclonal antibody.

Applications:

WB IHC

Background:

Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.

References:

[1] "Cloning and characterization of human tumor cell interstitial collagenase."Templeton N.S., Brown P.D., Levy A.T., Margulies I.M.K., Liotta L.A., Stetler-Stevenson W.G.Cancer Res. 50:5431-5437(1990) [PubMed: 2167156] [Abstract]Cited for: NUCLEOTIDE SE

appl_detail:

Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200

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