Macrophage migration inhibitory factor Polyclonal Antibody

Catalog Number:

42468

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P14174

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Macrophage migration inhibitory factor protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Macrophage migration inhibitory factor polyclonal antibody.

Applications:

WB

Background:

Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

References:

[1] "Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor."Weiser W.Y., Temple P.A., Witek-Giannotti J.S., Remold H.G., Clark S.C., David J.R.Proc. Natl. Acad. Sci. U.S.A. 86:7522-7526(1989) [2] "Molecular cloning and func

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF