C-C motif chemokine 22 Polyclonal Antibody

Catalog Number:

42443

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O00626

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human C-C motif chemokine 22 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total C-C motif chemokine 22 polyclonal antibody.

Applications:

WB

Background:

May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.

References:

[1] "Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes."Chang M.-S., McNinch J., Elias C. III, Manthey C.L., Grosshans D., Meng T., B

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF