Cyclin-dependent kinase 11A Polyclonal Antibody

Catalog Number:

42427

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UQ88

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Cyclin-dependent kinase 11A protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Cyclin-dependent kinase 11A polyclonal antibody.

Applications:

WB

Background:

Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.

References:

[1] "Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms." Xiang J., Lahti J.M., Grenet J.A., Easton J.B., Kidd V.J. J. Biol. Chem. 269:15786-15794(1994) [PubMed: 8195233] [Abstract] Cited for: NUCLEOTIDE SEQUENCE

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF