Metalloproteinase inhibitor 3 Polyclonal Antibody

Catalog Number:

42548

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P35625

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Metalloproteinase inhibitor 3 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Metalloproteinase inhibitor 3 polyclonal antibody.

Applications:

WB IHC

Background:

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

References:

[1] "Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family."Uria J.A., Ferrando A.A., Velasco G., Freije J.M., Lopez-Otin C.Cancer Res. 54:2091-2094(1994) [2] "Cloning and chara

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF