Vesicle-associated membrane protein 7 Polyclonal Antibody

Catalog Number:

42365

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P51809

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Vesicle-associated membrane protein 7 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Vesicle-associated membrane protein 7 polyclonal antibody.

Applications:

IHC

Background:

Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation.

References:

[1]"A synaptobrevin-like gene in the Xq28 pseudoautosomal region undergoes X inactivation."D'Esposito M., Ciccodicola A., Gianfrancesco F., Esposito T., Flagiello L., Mazzarella R., Schlessinger D., D'Urso M.Nat. Genet. 13:227-229(1996)

appl_detail:

Immunohistochemistry: 1:20 - 1:200

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