Toll-like receptor 7 Polyclonal Antibody

Catalog Number:

42344

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P58681

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant mouse Toll-like receptor 7 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Toll-like receptor 7 polyclonal antibody.

Applications:

IHC

Background:

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response

References:

[1]Molecular cloning of murine Toll-like receptor 7.Heil F.J., Lipford G.B., Wagner H., Bauer S.M.Submitted (MAY-2001) [2]Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.Diebold S.S., Kaisho T., Hemmi H., Akira S.

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF