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SRI Polyclonal Antibody

Catalog Number:

42331
other_names: Sorcin, 22 kDa protein, CP-22, CP22, V19, SRI

Amount:

100μg
calculated_mw: 22kd
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P30626

Form of Antibody:

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage/Stability:

Immunogen:

Recombinant human Sorcin protein(1-198aa)

Purification:

Antigen Affinity Purified

Specificity/Sensitivity:

The antibody detects endogenous level of total SRI polyclonal antibody.

Applications:

WB IHC

Background:

Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.

References:

[1]Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor."Franceschini S., Ilari A., Verzili D., Zamparelli C., Antaramian A., R

appl_detail:

Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200

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