40S ribosomal protein SA Polyclonal Antibody

Catalog Number:

42314

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P08865

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human 40S ribosomal protein SA protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total 40S ribosomal protein SA polyclonal antibody.

Applications:

WB

Background:

Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.

References:

[1]"Crystal structure of the human laminin receptor precursor."Jamieson K.V., Wu J., Hubbard S.R., Meruelo D.J. Biol. Chem. 283:3002-3005(2008).[2]"Initial characterization of the human central proteome."Burkard T.R., Planyavsky

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF