Zinc finger protein 91 Polyclonal Antibody

Catalog Number:

42310

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q05481

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Zinc finger protein 91 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Zinc finger protein 91 polyclonal antibody.

Applications:

IHC

Background:

Transcription factor specifically required to repress SINE-VNTR-Alu (SVA) retrotransposons: recognizes and binds SVA sequences and represses their expression by recruiting a repressive complex containing TRIM28/KAP1 (PubMed:25274305). May also bind the promoter of the FCGR2B gene, leading to repress its expression; however, additional evidences are required to confirm this result in vivo (PubMed:11470777).

References:

[1] Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.Bellefroid E.J., Marine J.-C., Ried T., Lecocq P.J., Riviere M., Amemiya C.T., Poncelet D.A., Coulie P.G., de Jong P.J., Szpirer C., Ward D.

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF