Ras-related protein Rab-5A Polyclonal Antibody

Catalog Number:

42305

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P20339

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Ras-related protein Rab-5A protein£¨1-215aa£©

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Ras-related protein Rab-5A polyclonal antibody.

Applications:

IHC

Background:

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension.

References:

[1]"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) . [2]"A quantitative atlas of mitotic phospho

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF