Nephrin Polyclonal Antibody

Catalog Number:

42273

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60500

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Nephrin protein£¨23-257aa£©

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Nephrin polyclonal antibody.

Applications:

IHC

Background:

Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.

References:

[1]Interaction with podocin facilitates nephrin signaling. Huber T.B., Kottgen M., Schilling B., Walz G., Benzing T. J. Biol. Chem. 276:41543-41546(2001). [2]Phosphoproteome of resting human platelets. Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF