Cytoplasmic protein NCK2 Polyclonal Antibody

Catalog Number:

42268

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O43639

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Cytoplasmic protein NCK2 protein£¨1-380aa£©

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Cytoplasmic protein NCK2 polyclonal antibody.

Applications:

IHC

Background:

Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.

References:

[1]"Solution structure of the SH3 domain of the human cytoplasmic protein NCK2." RIKEN structural genomics initiative (RSGI)Submitted (JUL-2005). [2]"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF