Prefoldin subunit 1 Polyclonal Antibody

Catalog Number:

42260

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60925

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Prefoldin subunit 1 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Prefoldin subunit 1 polyclonal antibody.

Applications:

IHC

Background:

PFDN1 is a heterohexameric chaperone protein which assists in the correct folding of other proteins. It binds specifically to cytosolic chaperonin and transfers target proteins. PFDN1 may function by selectively targeting nascent actin and tubulin chains pending their transfer to cytosolic chaperonin for final folding and/or assembly. It promotes folding in an environment in which there are many competing pathways for non native proteins.

References:

[1] "Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin."Vainberg I.E., Lewis S.A., Rommelaere H., Ampe C., Vandekerckhove J., Klein H.L., Cowan N.J.Cell 93:863-873(1998) [2] "Complete sequencing and characterization of 21,24

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF