Heterogeneous nuclear ribonucleoprotein H Polyclonal Antibody

Catalog Number:

42411

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P31943

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human DNA-directed RNA polymerases I, II, and III subunit RPABC2 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Heterogeneous nuclear ribonucleoprotein H polyclonal antibody.

Applications:

WB

Background:

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and togther with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds.

References:

[1] "A 14.4 KDa acidic subunit of human RNA polymerase II with a putative leucine-zipper." Acker J., Wintzerith M., Vigneron M., Kedinger C. DNA Seq. 4:329-331(1994) [PubMed: 7803819] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [2] "G

appl_detail:

Western blotting: 1:500 - 1:1000

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